KPV 10 mg

KPV — Targeted Anti-Inflammatory Peptide

KPV (Lysine–Proline–Valine) is a short-chain peptide derived from the terminal segment of alpha-melanocyte stimulating hormone (α-MSH). Although it consists of only three amino acids, it maintains key biological properties associated with anti-inflammatory activity. Its compact structure contributes to increased stability and allows for efficient interaction within biological systems, making it a useful compound in inflammation-focused research.

Mechanism of Action

Research suggests KPV influences inflammatory pathways through several biological processes. It has been observed to limit activation of NF-κB signaling by interfering with upstream regulatory steps, which in turn may reduce the expression of inflammatory cytokines such as IL-1β, IL-6, and TNF-α. KPV may also play a role in regulating immune cell response and movement. While it shows some interaction with melanocortin receptors, evidence indicates its activity is not solely dependent on these pathways. Its ability to interact with epithelial barriers has made it a subject of interest in gastrointestinal and mucosal research models.

Research Applications

• Investigation of NF-κB signaling pathways
• Studies on intestinal barrier integrity and mucosal systems
• Cytokine response and inflammatory marker modulation
• Gastrointestinal inflammation pathway research
• Skin-related inflammation and tissue recovery models
• Comparative peptide studies alongside α-MSH

• Product Specifications

  • Quantity: Per vial
  • Purity: ≥99% (verified via HPLC)
  • Form: Lyophilized powder
  • Storage: Store refrigerated after reconstitution
  • Testing: Third-party lab tested in the USA, COA available

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  Intended for laboratory research use only. Not for human or animal consumption.